| Date | Home | Away | Result |
|---|---|---|---|
| 21/05/11 17:00 | FC Malaga | FC Barcelona | 1-3 |
| 21/05/11 19:00 | Hercules Alicante | Sporting Gijon | 0-0 |
| 21/05/11 19:00 | Real Madrid | UD Almeria | 8-1 |
| 21/05/11 21:00 | CA Osasuna | FC Villarreal | 1-0 |
| 21/05/11 21:00 | Real Sociedad | FC Getafe | 1-1 |
| 21/05/11 21:00 | Espanyol Barcelona | FC Sevilla | 2-3 |
| 21/05/11 21:00 | UD Levante | Real Saragossa | 1-2 |
| 21/05/11 21:00 | RCD Mallorca | Atletico Madrid | 3-4 |
| 21/05/11 21:00 | Deportivo La Coruna | FC Valencia | 0-2 |
| 21/05/11 21:00 | Racing Santander | Athletic Bilbao | 1-2 |