| Date | Home | Away | Result |
|---|---|---|---|
| 15/05/21 16:00 | Caykur Rizespor | Istanbul Basaksehir FK | 0-2 |
| 15/05/21 16:00 | Fatih Karagümrük | Denizlispor | 5-1 |
| 15/05/21 16:00 | Antalyaspor | Konyaspor | 0-0 |
| 15/05/21 16:00 | Sivasspor | Kasimpasa Istanbul | 2-1 |
| 15/05/21 16:00 | MKE Ankaragücü | Alanyaspor | 0-1 |
| 15/05/21 16:00 | Hatayspor | Gazisehir Gaziantep FK | 0-1 |
| 15/05/21 18:30 | Trabzonspor | Genclerbirligi Ankara | 2-1 |
| 15/05/21 18:30 | Kayserispor | Fenerbahce Istanbul | 1-2 |
| 15/05/21 18:30 | Göztepe Izmir | Besiktas Istanbul | 1-2 |
| 15/05/21 18:30 | Galatasaray Istanbul | Yeni Malatyaspor | 3-1 |