| Date | Home | Away | Result |
|---|---|---|---|
| 23/05/21 16:00 | Aston Villa | Chelsea FC | 2-1 |
| 23/05/21 16:00 | Fulham FC | Newcastle United | 0-2 |
| 23/05/21 16:00 | Leeds United | West Bromwich Albion | 3-1 |
| 23/05/21 16:00 | Manchester City | Everton FC | 5-0 |
| 23/05/21 16:00 | West Ham United | Southampton FC | 3-0 |
| 23/05/21 16:00 | Wolverhampton Wanderers | Manchester United | 1-2 |
| 23/05/21 16:00 | Sheffield United | Burnley FC | 1-0 |
| 23/05/21 16:00 | Liverpool FC | Crystal Palace | 2-0 |
| 23/05/21 16:00 | Leicester City | Tottenham Hotspur | 2-4 |
| 23/05/21 16:00 | Arsenal FC | Brighton and Hove Albion | 2-0 |