| Date | Home | Away | Result |
|---|---|---|---|
| 23/05/21 20:00 | SCO Angers | OSC Lille | 1-2 |
| 23/05/21 20:00 | FC Nantes | HSC Montpellier | 1-2 |
| 23/05/21 20:00 | Stade Brest 29 | Paris St. Germain | 0-2 |
| 23/05/21 20:00 | FC Metz | Olympique Marseille | 1-1 |
| 23/05/21 20:00 | RC Lens | AS Monaco | 0-0 |
| 23/05/21 20:00 | Racing Club Strasbourg | FC Lorient | 1-1 |
| 23/05/21 20:00 | Olympique Lyon | OGC Nice | 2-3 |
| 23/05/21 20:00 | Stade Reims | Girondins Bordeaux | 1-2 |
| 23/05/21 20:00 | Stade Rennes | Nimes Olympique | 2-0 |
| 23/05/21 20:00 | AS St. Etienne | Dijon FCO | 0-1 |