| Date | Dead line | Home | Away | Result | Points rule |
|---|
| 02/09/22 19:30 | 02/09/22 19:25 | Borussia Dortmund | 1899 Hoffenheim | 1-0 | 2 - 4 points |
| 03/09/22 14:30 | 03/09/22 14:25 | VfL Wolfsburg | 1. FC Köln | 2-4 | 2 - 4 points |
| 03/09/22 14:30 | 03/09/22 14:25 | 1. FC Union Berlin | FC Bayern Munich | 1-1 | 2 - 4 points |
| 03/09/22 14:30 | 03/09/22 14:25 | VfB Stuttgart | FC Schalke 04 | 1-1 | 2 - 4 points |
| 03/09/22 14:30 | 03/09/22 14:25 | Bayer 04 Leverkusen | SC Freiburg | 2-3 | 2 - 4 points |
| 03/09/22 14:30 | 03/09/22 14:25 | VfL Bochum | Werder Bremen | 0-2 | 2 - 4 points |
| 03/09/22 17:30 | 03/09/22 17:25 | Eintracht Frankfurt | RB Leipzig | 4-0 | 2 - 4 points |
| 04/09/22 14:30 | 04/09/22 14:25 | FC Augsburg | Hertha BSC | 0-2 | 2 - 4 points |
| 04/09/22 16:30 | 04/09/22 16:25 | Bor. Mönchengladbach | FSV Mainz 05 | 0-1 | 2 - 4 points |
