| Date | Home | Away | Result |
|---|---|---|---|
| 31/07/20 20:00 | Virtus Entella | AS Cittadella | 2-3 |
| 31/07/20 20:00 | Cosenza Calcio | Juve Stabia | 3-1 |
| 31/07/20 20:00 | US Salernitana | Spezia Calcio | 1-2 |
| 31/07/20 20:00 | FC Venice | AC Perugia | 3-1 |
| 31/07/20 20:00 | Ascoli Calcio | Benevento Calcio | 2-4 |
| 31/07/20 20:00 | AS Livorno | FC Empoli | 0-2 |
| 31/07/20 20:00 | Trapani Calcio | FC Crotone | 2-0 |
| 31/07/20 20:00 | Frosinone Calcio | AC Pisa | 1-1 |
| 31/07/20 20:00 | US Cremonese | Pordenone | 2-2 |
| 31/07/20 20:00 | AC Chievo Verona | Pescara Calcio | 1-0 |