| Date | Home | Away | Result |
|---|---|---|---|
| 17/03/19 17:00 | KV Kortrijk | Royal Antwerp FC | 2-0 |
| 17/03/19 17:00 | SV Zulte-Waregem | KRC Genk | 3-3 |
| 17/03/19 17:00 | Standard Liège | Waasland-Beveren | 4-3 |
| 17/03/19 17:00 | KV Oostende | RSC Anderlecht | 0-2 |
| 17/03/19 17:00 | Sporting Charleroi | KAS Eupen | 1-2 |
| 17/03/19 17:00 | Sint-Truidense VV | KAA Gent | 0-2 |
| 17/03/19 17:00 | Club Brugge | Royal Excel Mouscron | 1-2 |
| 17/03/19 17:00 | KSC Lokeren OV | KSV Cercle Brügge | 3-1 |