Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 14/09/21 19:45 | 14/09/21 19:45 | Blackburn Rovers | Hull City A.F.C. | 2-0 | 3 - 6 - 10 |
| 14/09/21 19:45 | 14/09/21 19:45 | FC Blackpool | Huddersfield Town | 0-3 | 4 - 5 - 5 |
| 14/09/21 19:45 | 14/09/21 19:45 | AFC Bournemouth | Queens Park Rangers | 2-1 | 4 - 6 - 10 |
| 14/09/21 19:45 | 14/09/21 19:45 | Sheffield United | Preston North End | 2-2 | 3 - 8 - 8 |
| 14/09/21 20:00 | 14/09/21 20:00 | Reading FC | Peterborough United | 3-1 | 4 - 6 - 10 |
| 14/09/21 20:00 | 14/09/21 20:00 | West Bromwich Albion | Derby County | 0-0 | 3 - 10 - 10 |
| 15/09/21 19:45 | 15/09/21 19:45 | Coventry City | Cardiff City | 1-0 | 4 - 6 - 6 |
| 15/09/21 19:45 | 15/09/21 19:45 | Swansea City | Millwall FC | 0-0 | 4 - 6 - 7 |
| 15/09/21 19:45 | 15/09/21 19:45 | Birmingham City | Fulham FC | 1-4 | 6 - 5 - 4 |
| 15/09/21 19:45 | 15/09/21 19:45 | Bristol City | Luton Town | 1-1 | 4 - 5 - 6 |
| 15/09/21 19:45 | 15/09/21 19:45 | Nottingham Forest | Middlesbrough FC | 0-2 | 5 - 6 - 4 |
| 15/09/21 19:45 | 15/09/21 19:45 | Stoke City | Barnsley FC | 1-1 | 3 - 10 - 10 |