Schedule
| Competition | Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|---|
| 2.BL | 11/09/21 12:30 | 11/09/21 12:30 | FC Ingolstadt | Werder Bremen | 0-3 | 4 - 7 - 2 |
| 2.BL | 11/09/21 12:30 | 11/09/21 12:30 | Karlsruher SC | Holstein Kiel | 2-2 | 2 - 7 - 4 |
| 2.BL | 11/09/21 12:30 | 11/09/21 12:30 | Hannover 96 | FC St. Pauli | 1-0 | 7 - 4 - 2 |
| 2.BL | 11/09/21 19:30 | 11/09/21 19:30 | Hamburger SV | SV Sandhausen | 2-1 | 2 - 7 - 7 |
| 2.BL | 12/09/21 12:30 | 12/09/21 12:30 | Jahn Regensburg | 1. FC Nürnberg | 2-2 | 3 - 3 - 3 |
| 2.BL | 12/09/21 12:30 | 12/09/21 12:30 | FC Hansa Rostock | SV Darmstadt 98 | 2-1 | 7 - 3 - 3 |
| 2.BL | 12/09/21 12:30 | 12/09/21 12:30 | 1. FC Heidenheim 1846 | Dynamo Dresden | 2-1 | 3 - 4 - 3 |
| 2.BL | 12/09/21 12:30 | 12/09/21 12:30 | SC Paderborn 07 | FC Schalke 04 | 0-1 | 3 - 7 - 3 |
| 2.BL | 12/09/21 12:30 | 12/09/21 12:30 | Erzgebirge Aue | Fortuna Düsseldorf | 0-1 | 4 - 4 - 3 |