Schedule
| Competition | Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|---|
| 2.BL | 15/10/21 17:30 | 15/10/21 17:30 | SC Paderborn 07 | Jahn Regensburg | 1-1 | 3 - 5 - 4 |
| 2.BL | 15/10/21 17:30 | 15/10/21 17:30 | Hannover 96 | FC Schalke 04 | 0-1 | 5 - 7 - 2 |
| 2.BL | 16/10/21 12:30 | 16/10/21 12:30 | 1. FC Heidenheim 1846 | FC St. Pauli | 2-4 | 3 - 5 - 3 |
| 2.BL | 16/10/21 12:30 | 16/10/21 12:30 | FC Ingolstadt | Holstein Kiel | 1-1 | 7 - 3 - 3 |
| 2.BL | 16/10/21 12:30 | 16/10/21 12:30 | Karlsruher SC | Erzgebirge Aue | 2-1 | 2 - 5 - 5 |
| 2.BL | 16/10/21 19:30 | 16/10/21 19:30 | Hamburger SV | Fortuna Düsseldorf | 1-1 | 2 - 7 - 4 |
| 2.BL | 17/10/21 12:30 | 17/10/21 12:30 | SV Darmstadt 98 | Werder Bremen | 3-0 | 4 - 7 - 2 |
| 2.BL | 17/10/21 12:30 | 17/10/21 12:30 | Dynamo Dresden | 1. FC Nürnberg | 0-1 | 5 - 3 - 3 |
| 2.BL | 17/10/21 12:30 | 17/10/21 12:30 | FC Hansa Rostock | SV Sandhausen | 1-1 | 2 - 7 - 5 |