Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 01/03/22 19:45 | 01/03/22 19:45 | 1. FC Union Berlin | FC St. Pauli | 2-1 | 2 - 4 points |
| 02/03/22 17:30 | 02/03/22 17:30 | Hamburger SV | Karlsruher SC | 5-4a.PSO | 2 - 4 points |
| 02/03/22 17:30 | 02/03/22 17:30 | Hannover 96 | RB Leipzig | 0-4 | 2 - 4 points |
| 02/03/22 19:45 | 02/03/22 19:45 | VfL Bochum | SC Freiburg | 1-2a.e.t | 2 - 4 points |