| Date | Home | Away | Result |
|---|---|---|---|
| 01/03/22 19:45 | 1. FC Union Berlin | FC St. Pauli | 2-1 |
| 02/03/22 17:30 | Hamburger SV | Karlsruher SC | 5-4a.PSO |
| 02/03/22 17:30 | Hannover 96 | RB Leipzig | 0-4 |
| 02/03/22 19:45 | VfL Bochum | SC Freiburg | 1-2a.e.t |
| Date | Home | Away | Result |
|---|---|---|---|
| 01/03/22 19:45 | 1. FC Union Berlin | FC St. Pauli | 2-1 |
| 02/03/22 17:30 | Hamburger SV | Karlsruher SC | 5-4a.PSO |
| 02/03/22 17:30 | Hannover 96 | RB Leipzig | 0-4 |
| 02/03/22 19:45 | VfL Bochum | SC Freiburg | 1-2a.e.t |