Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 20/08/21 18:00 | 20/08/21 18:00 | Viktoria 1889 Berlin | Hallescher FC | 0-1 | 5 - 7 points |
| 21/08/21 13:00 | 21/08/21 13:00 | 1. FC Kaiserslautern | TSV 1860 Munich | 3-0 | 5 - 7 points |
| 21/08/21 13:00 | 21/08/21 13:00 | 1. FC Magdeburg | MSV Duisburg | 2-1 | 5 - 7 points |
| 21/08/21 13:00 | 21/08/21 13:00 | Eintracht Braunschweig | FSV Zwickau | 2-0 | 5 - 7 points |
| 21/08/21 13:00 | 21/08/21 13:00 | FC Viktoria Köln | SV Waldhof Mannheim | 2-3 | 5 - 7 points |
| 21/08/21 13:00 | 21/08/21 13:00 | SV Meppen | SC Verl | 2-0 | 5 - 7 points |
| 21/08/21 13:00 | 21/08/21 13:00 | Borussia Dortmund II | 1. FC Saarbrücken | 0-0 | 5 - 7 points |
| 22/08/21 12:00 | 22/08/21 12:00 | FC Würzburger Kickers | VfL Osnabrück | 1-1 | 5 - 7 points |
| 22/08/21 13:00 | 22/08/21 13:00 | SV Wehen Wiesbaden | TSV Havelse | 2-1 | 5 - 7 points |
| 22/08/21 14:00 | 22/08/21 14:00 | Türkgücü München | SC Freiburg II | 3-0 | 5 - 7 points |