Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 08/04/22 18:00 | 08/04/22 18:00 | FC Würzburger Kickers | 1. FC Kaiserslautern | 1-2 | 5 - 7 points |
| 09/04/22 13:00 | 09/04/22 13:00 | MSV Duisburg | Hallescher FC | 2-1 | 5 - 7 points |
| 09/04/22 13:00 | 09/04/22 13:00 | 1. FC Magdeburg | FC Viktoria Köln | 4-2 | 5 - 7 points |
| 09/04/22 13:00 | 09/04/22 13:00 | Borussia Dortmund II | Viktoria 1889 Berlin | 0-1 | 5 - 7 points |
| 09/04/22 13:00 | 09/04/22 13:00 | 1. FC Saarbrücken | SV Waldhof Mannheim | 0-0 | 5 - 7 points |
| 09/04/22 13:00 | 09/04/22 13:00 | SV Wehen Wiesbaden | Eintracht Braunschweig | 0-1 | 5 - 7 points |
| 10/04/22 12:00 | 10/04/22 12:00 | SC Freiburg II | TSV 1860 Munich | 1-2 | 5 - 7 points |
| 10/04/22 13:00 | 10/04/22 13:00 | TSV Havelse | FSV Zwickau | 0-3 | 5 - 7 points |
| 11/04/22 18:00 | 11/04/22 18:00 | VfL Osnabrück | SC Verl | 3-2 | 5 - 7 points |