Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 01/04/22 18:00 | 01/04/22 18:00 | SV Meppen | SV Wehen Wiesbaden | 0-4 | 5 - 7 points |
| 02/04/22 13:00 | 02/04/22 13:00 | FC Viktoria Köln | Borussia Dortmund II | 0-2 | 5 - 7 points |
| 02/04/22 13:00 | 02/04/22 13:00 | SC Verl | SC Freiburg II | 3-1 | 5 - 7 points |
| 02/04/22 13:00 | 02/04/22 13:00 | 1. FC Kaiserslautern | MSV Duisburg | 5-1 | 5 - 7 points |
| 02/04/22 13:00 | 02/04/22 13:00 | Eintracht Braunschweig | TSV Havelse | 3-2 | 5 - 7 points |
| 02/04/22 13:00 | 02/04/22 13:00 | TSV 1860 Munich | 1. FC Saarbrücken | 1-1 | 5 - 7 points |
| 03/04/22 12:00 | 03/04/22 12:00 | FSV Zwickau | SV Waldhof Mannheim | 1-1 | 5 - 7 points |
| 04/04/22 18:00 | 04/04/22 18:00 | Viktoria 1889 Berlin | 1. FC Magdeburg | 2-1 | 5 - 7 points |
| 19/04/22 18:00 | 19/04/22 18:00 | Hallescher FC | VfL Osnabrück | 3-3 | 5 - 7 points |