Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 04/03/22 18:00 | 04/03/22 18:00 | TSV 1860 Munich | SC Verl | 2-0 | 5 - 7 points |
| 05/03/22 13:00 | 05/03/22 13:00 | SC Freiburg II | FSV Zwickau | 1-0 | 5 - 7 points |
| 05/03/22 13:00 | 05/03/22 13:00 | SV Wehen Wiesbaden | FC Würzburger Kickers | 0-1 | 5 - 7 points |
| 05/03/22 13:00 | 05/03/22 13:00 | VfL Osnabrück | 1. FC Kaiserslautern | 0-1 | 5 - 7 points |
| 05/03/22 13:00 | 05/03/22 13:00 | MSV Duisburg | FC Viktoria Köln | 2-0 | 5 - 7 points |
| 05/03/22 13:00 | 05/03/22 13:00 | Borussia Dortmund II | Türkgücü München | 0-1 | 5 - 7 points |
| 05/03/22 13:00 | 05/03/22 13:00 | 1. FC Magdeburg | Hallescher FC | 1-1 | 5 - 7 points |
| 06/03/22 12:00 | 06/03/22 12:00 | 1. FC Saarbrücken | SV Meppen | 1-0 | 5 - 7 points |
| 06/03/22 13:00 | 06/03/22 13:00 | SV Waldhof Mannheim | Eintracht Braunschweig | 0-3 | 5 - 7 points |
| 07/03/22 18:00 | 07/03/22 18:00 | TSV Havelse | Viktoria 1889 Berlin | 1-1 | 5 - 7 points |