Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 19/02/22 13:00 | 19/02/22 13:00 | SV Wehen Wiesbaden | Viktoria 1889 Berlin | 2-0 | 5 - 7 points |
| 19/02/22 13:00 | 19/02/22 13:00 | MSV Duisburg | Türkgücü München | 2-0 | 5 - 7 points |
| 19/02/22 13:00 | 19/02/22 13:00 | SC Freiburg II | SV Meppen | 2-0 | 5 - 7 points |
| 19/02/22 13:00 | 19/02/22 13:00 | 1. FC Saarbrücken | FC Viktoria Köln | 0-1 | 5 - 7 points |
| 19/02/22 13:00 | 19/02/22 13:00 | 1. FC Magdeburg | Borussia Dortmund II | 2-0 | 5 - 7 points |
| 20/02/22 12:00 | 20/02/22 12:00 | TSV Havelse | FC Würzburger Kickers | 1-3 | 5 - 7 points |
| 20/02/22 13:00 | 20/02/22 13:00 | SV Waldhof Mannheim | 1. FC Kaiserslautern | 0-0 | 5 - 7 points |
| 21/02/22 18:00 | 21/02/22 18:00 | TSV 1860 Munich | Hallescher FC | 0-2 | 5 - 7 points |
| 26/03/22 13:00 | 26/03/22 13:00 | VfL Osnabrück | Eintracht Braunschweig | 1-1 | 5 - 7 points |
| 29/03/22 18:00 | 29/03/22 18:00 | SC Verl | FSV Zwickau | 0-0 | 5 - 7 points |