Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 28/01/22 18:00 | 28/01/22 18:00 | FC Würzburger Kickers | SC Freiburg II | 1-1 | 5 - 7 points |
| 29/01/22 13:00 | 29/01/22 13:00 | 1. FC Kaiserslautern | Hallescher FC | 1-0 | 5 - 7 points |
| 29/01/22 13:00 | 29/01/22 13:00 | Türkgücü München | TSV Havelse | 0-1 | 5 - 7 points |
| 29/01/22 13:00 | 29/01/22 13:00 | Borussia Dortmund II | VfL Osnabrück | 2-2 | 5 - 7 points |
| 29/01/22 13:00 | 29/01/22 13:00 | SV Wehen Wiesbaden | MSV Duisburg | 0-1 | 5 - 7 points |
| 29/01/22 16:55 | 29/01/22 16:55 | 1. FC Magdeburg | 1. FC Saarbrücken | 2-1 | 5 - 7 points |
| 30/01/22 12:00 | 30/01/22 12:00 | FC Viktoria Köln | TSV 1860 Munich | 0-1 | 5 - 7 points |
| 30/01/22 13:00 | 30/01/22 13:00 | SV Meppen | SV Waldhof Mannheim | 1-1 | 5 - 7 points |
| 31/01/22 18:00 | 31/01/22 18:00 | Eintracht Braunschweig | SC Verl | 1-1 | 5 - 7 points |
| 16/03/22 18:00 | 16/03/22 18:00 | Viktoria 1889 Berlin | FSV Zwickau | 0-0 | 5 - 7 points |