Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 21/01/22 18:00 | 21/01/22 18:00 | Borussia Dortmund II | SC Freiburg II | 1-1 | 5 - 7 points |
| 22/01/22 13:00 | 22/01/22 13:00 | Eintracht Braunschweig | Hallescher FC | 1-0 | 5 - 7 points |
| 22/01/22 13:00 | 22/01/22 13:00 | 1. FC Kaiserslautern | Viktoria 1889 Berlin | 2-0 | 5 - 7 points |
| 22/01/22 13:00 | 22/01/22 13:00 | FC Viktoria Köln | SC Verl | 5-2 | 5 - 7 points |
| 22/01/22 13:00 | 22/01/22 13:00 | FC Würzburger Kickers | SV Waldhof Mannheim | 1-2 | 5 - 7 points |
| 22/01/22 13:00 | 22/01/22 13:00 | SV Wehen Wiesbaden | VfL Osnabrück | 0-0 | 5 - 7 points |
| 23/01/22 12:00 | 23/01/22 12:00 | SV Meppen | FSV Zwickau | 1-3 | 5 - 7 points |
| 23/01/22 13:00 | 23/01/22 13:00 | MSV Duisburg | 1. FC Saarbrücken | 3-4 | 5 - 7 points |
| 23/01/22 14:00 | 23/01/22 14:00 | 1. FC Magdeburg | TSV Havelse | 1-1 | 5 - 7 points |
| 16/02/22 18:00 | 16/02/22 18:00 | Türkgücü München | TSV 1860 Munich | 2-1 | 5 - 7 points |