Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 17/12/21 18:00 | 17/12/21 18:00 | FC Viktoria Köln | Viktoria 1889 Berlin | 1-4 | 5 - 7 points |
| 18/12/21 13:00 | 18/12/21 13:00 | SV Wehen Wiesbaden | SC Freiburg II | 2-0 | 5 - 7 points |
| 18/12/21 13:00 | 18/12/21 13:00 | 1. FC Saarbrücken | TSV Havelse | 2-2 | 5 - 7 points |
| 18/12/21 13:00 | 18/12/21 13:00 | Eintracht Braunschweig | 1. FC Kaiserslautern | 1-1 | 5 - 7 points |
| 18/12/21 13:00 | 18/12/21 13:00 | SV Meppen | Hallescher FC | 4-1 | 5 - 7 points |
| 18/12/21 13:00 | 18/12/21 13:00 | Türkgücü München | SC Verl | 2-2 | 5 - 7 points |
| 18/12/21 13:00 | 18/12/21 13:00 | Borussia Dortmund II | FSV Zwickau | 3-1 | 5 - 7 points |
| 19/12/21 12:00 | 19/12/21 12:00 | 1. FC Magdeburg | SV Waldhof Mannheim | 3-0 | 5 - 7 points |
| 20/12/21 18:00 | 20/12/21 18:00 | FC Würzburger Kickers | TSV 1860 Munich | 0-3 | 5 - 7 points |
| 02/02/22 18:00 | 02/02/22 18:00 | MSV Duisburg | VfL Osnabrück | 3-6 | 5 - 7 points |