Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 10/12/21 18:00 | 10/12/21 18:00 | Türkgücü München | 1. FC Kaiserslautern | 1-2 | 5 - 7 points |
| 11/12/21 13:00 | 11/12/21 13:00 | TSV Havelse | SV Waldhof Mannheim | 1-2 | 5 - 7 points |
| 11/12/21 13:00 | 11/12/21 13:00 | FC Viktoria Köln | Eintracht Braunschweig | 1-2 | 5 - 7 points |
| 11/12/21 13:00 | 11/12/21 13:00 | 1. FC Saarbrücken | SC Freiburg II | 1-0 | 5 - 7 points |
| 11/12/21 13:00 | 11/12/21 13:00 | Borussia Dortmund II | TSV 1860 Munich | 0-2 | 5 - 7 points |
| 11/12/21 13:00 | 11/12/21 13:00 | 1. FC Magdeburg | VfL Osnabrück | 2-1 | 5 - 7 points |
| 11/12/21 13:00 | 11/12/21 13:00 | MSV Duisburg | SC Verl | 2-2 | 5 - 7 points |
| 12/12/21 12:00 | 12/12/21 12:00 | SV Meppen | Viktoria 1889 Berlin | 3-0 | 5 - 7 points |
| 12/12/21 13:00 | 12/12/21 13:00 | FC Würzburger Kickers | FSV Zwickau | 2-2 | 5 - 7 points |
| 13/12/21 18:00 | 13/12/21 18:00 | SV Wehen Wiesbaden | Hallescher FC | 2-1 | 5 - 7 points |