Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 26/11/21 18:00 | 26/11/21 18:00 | MSV Duisburg | SV Waldhof Mannheim | 1-3 | 5 - 7 points |
| 27/11/21 13:00 | 27/11/21 13:00 | Borussia Dortmund II | 1. FC Kaiserslautern | 0-0 | 5 - 7 points |
| 27/11/21 13:00 | 27/11/21 13:00 | SV Wehen Wiesbaden | SC Verl | 0-0 | 5 - 7 points |
| 27/11/21 13:00 | 27/11/21 13:00 | FC Würzburger Kickers | SV Meppen | 1-3 | 5 - 7 points |
| 27/11/21 13:00 | 27/11/21 13:00 | TSV Havelse | TSV 1860 Munich | 2-3 | 5 - 7 points |
| 27/11/21 13:00 | 27/11/21 13:00 | 1. FC Saarbrücken | Viktoria 1889 Berlin | 2-0 | 5 - 7 points |
| 27/11/21 13:00 | 27/11/21 13:00 | 1. FC Magdeburg | Eintracht Braunschweig | 2-0 | 5 - 7 points |
| 28/11/21 12:00 | 28/11/21 12:00 | VfL Osnabrück | SC Freiburg II | 0-1 | 5 - 7 points |
| 28/11/21 13:00 | 28/11/21 13:00 | FC Viktoria Köln | Hallescher FC | 2-0 | 5 - 7 points |
| 29/11/21 18:00 | 29/11/21 18:00 | Türkgücü München | FSV Zwickau | 2-2 | 5 - 7 points |