Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 05/11/21 18:00 | 05/11/21 18:00 | Türkgücü München | FC Viktoria Köln | 1-2 | 5 - 7 points |
| 06/11/21 13:00 | 06/11/21 13:00 | 1. FC Saarbrücken | 1. FC Kaiserslautern | 0-2 | 5 - 7 points |
| 06/11/21 13:00 | 06/11/21 13:00 | SC Freiburg II | SV Waldhof Mannheim | 2-1 | 5 - 7 points |
| 06/11/21 13:00 | 06/11/21 13:00 | MSV Duisburg | Viktoria 1889 Berlin | 1-0 | 5 - 7 points |
| 06/11/21 13:00 | 06/11/21 13:00 | VfL Osnabrück | TSV 1860 Munich | 3-1 | 5 - 7 points |
| 06/11/21 13:00 | 06/11/21 13:00 | TSV Havelse | Hallescher FC | 2-1 | 5 - 7 points |
| 06/11/21 13:00 | 06/11/21 13:00 | Borussia Dortmund II | SV Meppen | 0-1 | 5 - 7 points |
| 07/11/21 12:00 | 07/11/21 12:00 | SV Wehen Wiesbaden | FSV Zwickau | 2-2 | 5 - 7 points |
| 07/11/21 13:00 | 07/11/21 13:00 | 1. FC Magdeburg | SC Verl | 2-0 | 5 - 7 points |
| 30/11/21 18:00 | 30/11/21 18:00 | FC Würzburger Kickers | Eintracht Braunschweig | 0-2 | 5 - 7 points |