Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 22/10/21 18:00 | 22/10/21 18:00 | VfL Osnabrück | Hallescher FC | 0-0 | 5 - 7 points |
| 23/10/21 13:00 | 23/10/21 13:00 | SV Waldhof Mannheim | FSV Zwickau | 1-1 | 5 - 7 points |
| 23/10/21 13:00 | 23/10/21 13:00 | 1. FC Magdeburg | Viktoria 1889 Berlin | 1-0 | 5 - 7 points |
| 23/10/21 13:00 | 23/10/21 13:00 | SV Wehen Wiesbaden | SV Meppen | 3-4 | 5 - 7 points |
| 23/10/21 13:00 | 23/10/21 13:00 | FC Würzburger Kickers | Türkgücü München | 2-1 | 5 - 7 points |
| 23/10/21 13:00 | 23/10/21 13:00 | 1. FC Saarbrücken | TSV 1860 Munich | 1-1 | 5 - 7 points |
| 23/10/21 13:00 | 23/10/21 13:00 | SC Freiburg II | SC Verl | 3-2 | 5 - 7 points |
| 24/10/21 12:00 | 24/10/21 12:00 | Borussia Dortmund II | FC Viktoria Köln | 0-1 | 5 - 7 points |
| 24/10/21 13:00 | 24/10/21 13:00 | TSV Havelse | Eintracht Braunschweig | 0-4 | 5 - 7 points |
| 25/10/21 18:00 | 25/10/21 18:00 | MSV Duisburg | 1. FC Kaiserslautern | 1-1 | 5 - 7 points |