Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 01/10/21 18:00 | 01/10/21 18:00 | 1. FC Saarbrücken | Eintracht Braunschweig | 2-2 | 5 - 7 points |
| 02/10/21 13:00 | 02/10/21 13:00 | TSV Havelse | 1. FC Kaiserslautern | 0-6 | 5 - 7 points |
| 02/10/21 13:00 | 02/10/21 13:00 | VfL Osnabrück | FSV Zwickau | 0-1 | 5 - 7 points |
| 02/10/21 13:00 | 02/10/21 13:00 | SC Freiburg II | Hallescher FC | 1-1 | 5 - 7 points |
| 02/10/21 13:00 | 02/10/21 13:00 | MSV Duisburg | SV Meppen | 0-1 | 5 - 7 points |
| 02/10/21 13:00 | 02/10/21 13:00 | TSV 1860 Munich | Viktoria 1889 Berlin | 1-1 | 5 - 7 points |
| 02/10/21 13:00 | 02/10/21 13:00 | SV Wehen Wiesbaden | FC Viktoria Köln | 1-1 | 5 - 7 points |
| 03/10/21 12:00 | 03/10/21 12:00 | Borussia Dortmund II | FC Würzburger Kickers | 2-0 | 5 - 7 points |
| 03/10/21 13:00 | 03/10/21 13:00 | SV Waldhof Mannheim | SC Verl | 2-1 | 5 - 7 points |
| 04/10/21 18:00 | 04/10/21 18:00 | 1. FC Magdeburg | Türkgücü München | 4-0 | 5 - 7 points |