Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 24/09/21 18:00 | 24/09/21 18:00 | Hallescher FC | 1. FC Magdeburg | 3-2 | 5 - 7 points |
| 25/09/21 13:00 | 25/09/21 13:00 | FC Viktoria Köln | MSV Duisburg | 4-2 | 5 - 7 points |
| 25/09/21 13:00 | 25/09/21 13:00 | FC Würzburger Kickers | SV Wehen Wiesbaden | 0-4 | 5 - 7 points |
| 25/09/21 13:00 | 25/09/21 13:00 | Eintracht Braunschweig | SV Waldhof Mannheim | 0-0 | 5 - 7 points |
| 25/09/21 13:00 | 25/09/21 13:00 | 1. FC Kaiserslautern | VfL Osnabrück | 2-0 | 5 - 7 points |
| 25/09/21 13:00 | 25/09/21 13:00 | SV Meppen | 1. FC Saarbrücken | 2-2 | 5 - 7 points |
| 25/09/21 13:00 | 25/09/21 13:00 | SC Verl | TSV 1860 Munich | 1-1 | 5 - 7 points |
| 26/09/21 12:00 | 26/09/21 12:00 | Türkgücü München | Borussia Dortmund II | 2-1 | 5 - 7 points |
| 26/09/21 13:00 | 26/09/21 13:00 | FSV Zwickau | SC Freiburg II | 0-0 | 5 - 7 points |
| 27/09/21 18:00 | 27/09/21 18:00 | Viktoria 1889 Berlin | TSV Havelse | 3-4 | 5 - 7 points |