Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 25/09/21 13:00 | 25/09/21 13:00 | SC Naumburg | MSV Eisleben | 2-3 | 1 - 3 points |
| 25/09/21 14:00 | 25/09/21 14:00 | ESV Herrengosserstedt | SV Burgwerben | 3-2 | 1 - 3 points |
| 25/09/21 14:00 | 25/09/21 14:00 | 1. FC Zeitz | BSC 99 Laucha | 3-0 | 1 - 3 points |
| 25/09/21 14:00 | 25/09/21 14:00 | SV Spora | FC RSK Freyburg | 0-0 | 1 - 3 points |
| 25/09/21 14:00 | 25/09/21 14:00 | Baumersrodaer SV | SG Bad Bibra/Saubach | 5-0 | 1 - 3 points |
| 25/09/21 14:00 | 25/09/21 14:00 | SV Kaiserpfalz | Reinsdorfer SV | 3-2 | 1 - 3 points |
| 26/09/21 13:00 | 26/09/21 13:00 | SC Naumburg II | FC ZWK Nebra | 1-1 | 1 - 3 points |
| 26/09/21 13:00 | 26/09/21 13:00 | Blau-Weiß Bad Kösen | Grün-Gelb Osterfeld | 6-0 | 1 - 3 points |
| 26/09/21 13:00 | 26/09/21 13:00 | Lossa/Rastenberg | Eintracht Profen | 0-4 | 1 - 3 points |
| 26/09/21 14:00 | 26/09/21 14:00 | TSV Großkorbetha | SV Mertendorf | 4-0 | 1 - 3 points |