Schedule
| Competition | Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|---|
| 21/22 | 06/10/21 12:00 | 06/10/21 12:00 | Usakspor | 24Erzincanspor | 1-0 | 1 - 3 points |
| 21/22 | 06/10/21 13:00 | 06/10/21 13:00 | Ankara Demirspor | Zonguldak Kömürspor | 2-2 | 1 - 3 points |
| 21/22 | 06/10/21 13:00 | 06/10/21 13:00 | Kirsehir Bel.spor | KT 1922 Konyaspor | 1-2 | 1 - 3 points |
| 21/22 | 06/10/21 13:30 | 06/10/21 13:30 | Pendikspor | Tarsus Idman Yurdu | 3-2 | 1 - 3 points |
| 21/22 | 06/10/21 13:30 | 06/10/21 13:30 | Nazilli Bel.spor | Bucaspor 1928 | 1-0 | 1 - 3 points |
| 21/22 | 06/10/21 17:00 | 06/10/21 17:00 | Akhisarspor | Isparta 32spor | 0-1 | 1 - 3 points |
| 21/22 | 06/10/21 17:00 | 06/10/21 17:00 | Sanliurfaspor | Pazarspor | 0-1 | 1 - 3 points |
| 21/22 | 06/10/21 17:00 | 06/10/21 17:00 | Karacabey Bel. Spor | Amed SF | 2-1 | 1 - 3 points |
| 21/22 | 10/10/21 12:30 | 10/10/21 12:30 | 24Erzincanspor | Kirsehir Bel.spor | 1-1 | 1 - 3 points |
| 21/22 | 10/10/21 12:30 | 10/10/21 12:30 | Pazarspor | Kirklarelispor | 1-1 | 1 - 3 points |
| 21/22 | 10/10/21 13:00 | 10/10/21 13:00 | KT 1922 Konyaspor | Nazilli Bel.spor | 1-1 | 1 - 3 points |
| 21/22 | 10/10/21 13:00 | 10/10/21 13:00 | Zonguldak Kömürspor | Eskisehirspor | 3-1 | 1 - 3 points |
| 21/22 | 10/10/21 17:00 | 10/10/21 17:00 | Bucaspor 1928 | Ankara Demirspor | 2-1 | 1 - 3 points |
| 21/22 | 10/10/21 17:00 | 10/10/21 17:00 | Amed SF | Sanliurfaspor | 2-2 | 1 - 3 points |
| 21/22 | 10/10/21 17:00 | 10/10/21 17:00 | Tarsus Idman Yurdu | Usakspor | 1-1 | 1 - 3 points |
| 21/22 | 10/10/21 17:00 | 10/10/21 17:00 | Isparta 32spor | Pendikspor | 0-1 | 1 - 3 points |
| TR1 | 15/10/21 18:00 | 15/10/21 18:00 | Istanbul Basaksehir FK | Besiktas Istanbul | 3-2 | 1 - 3 points |
| TR1 | 16/10/21 11:30 | 16/10/21 11:30 | Giresunspor | Caykur Rizespor | 2-0 | 1 - 3 points |
| 21/22 | 16/10/21 12:00 | 16/10/21 12:00 | Pendikspor | Akhisarspor | 4-1 | 1 - 3 points |
| 21/22 | 16/10/21 12:00 | 16/10/21 12:00 | Ankara Demirspor | KT 1922 Konyaspor | 1-0 | 1 - 3 points |
| TR1 | 16/10/21 14:00 | 16/10/21 14:00 | Sivasspor | Antalyaspor | 2-2 | 1 - 3 points |
| TR1 | 16/10/21 17:00 | 16/10/21 17:00 | Adana Demirspor | Yeni Malatyaspor | 0-2 | 1 - 3 points |
| TR1 | 17/10/21 11:30 | 17/10/21 11:30 | Kasimpasa Istanbul | Göztepe Izmir | 1-2 | 1 - 3 points |
| 21/22 | 17/10/21 12:00 | 17/10/21 12:00 | Kirklarelispor | Amed SF | 1-1 | 1 - 3 points |
| 21/22 | 17/10/21 12:00 | 17/10/21 12:00 | Kirsehir Bel.spor | Tarsus Idman Yurdu | 2-1 | 1 - 3 points |
| 21/22 | 17/10/21 12:00 | 17/10/21 12:00 | Usakspor | Isparta 32spor | 0-1 | 1 - 3 points |
| 21/22 | 17/10/21 12:00 | 17/10/21 12:00 | Nazilli Bel.spor | 24Erzincanspor | 1-1 | 1 - 3 points |
| TR1 | 17/10/21 14:00 | 17/10/21 14:00 | Altay SK | Fatih Karagümrük | 0-1 | 1 - 3 points |
| TR1 | 17/10/21 14:00 | 17/10/21 14:00 | Galatasaray Istanbul | Konyaspor | 1-0 | 1 - 3 points |
| TR1 | 17/10/21 17:00 | 17/10/21 17:00 | Trabzonspor | Fenerbahce Istanbul | 3-1 | 1 - 3 points |
| 21/22 | 17/10/21 17:00 | 17/10/21 17:00 | Karacabey Bel. Spor | Zonguldak Kömürspor | 1-2 | 1 - 3 points |
| 21/22 | 17/10/21 17:00 | 17/10/21 17:00 | Eskisehirspor | Bucaspor 1928 | 0-4 | 1 - 3 points |
| TR1 | 18/10/21 18:00 | 18/10/21 18:00 | Hatayspor | Gazisehir Gaziantep FK | 2-1 | 1 - 3 points |
| TR1 | 18/10/21 18:00 | 18/10/21 18:00 | Alanyaspor | Kayserispor | 6-3 | 1 - 3 points |