Schedule
| Competition | Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|---|
| 21/22 | 05/09/21 11:00 | 05/09/21 11:00 | Karacabey Bel. Spor | Eskisehirspor | 1-2 | 1 - 3 points |
| 21/22 | 05/09/21 11:00 | 05/09/21 11:00 | Sanliurfaspor | Ankara Demirspor | 1-0 | 1 - 3 points |
| 21/22 | 05/09/21 11:00 | 05/09/21 11:00 | Zonguldak Kömürspor | Akhisarspor | 0-1 | 1 - 3 points |
| 21/22 | 05/09/21 11:00 | 05/09/21 11:00 | Kirklarelispor | Nazilli Bel.spor | 1-3 | 1 - 3 points |
| 21/22 | 05/09/21 11:00 | 05/09/21 11:00 | KT 1922 Konyaspor | Tarsus Idman Yurdu | 0-0 | 1 - 3 points |
| 21/22 | 05/09/21 11:00 | 05/09/21 11:00 | Bucaspor 1928 | Isparta 32spor | 1-1 | 1 - 3 points |
| 21/22 | 05/09/21 11:00 | 05/09/21 11:00 | GMG Kastamonuspor | Pendikspor | --- | 1 - 3 points |
| 21/22 | 05/09/21 11:00 | 05/09/21 11:00 | Pazarspor | Kirsehir Bel.spor | 0-3 | 1 - 3 points |
| 21/22 | 05/09/21 11:00 | 05/09/21 11:00 | Amed SF | Usakspor | 3-1 | 1 - 3 points |
| 21/22 | 11/09/21 13:00 | 11/09/21 13:00 | Ankara Demirspor | Kirklarelispor | 1-0 | 1 - 3 points |
| 21/22 | 11/09/21 13:30 | 11/09/21 13:30 | Pendikspor | Zonguldak Kömürspor | 3-2 | 1 - 3 points |
| TR1 | 11/09/21 15:00 | 11/09/21 15:00 | Fatih Karagümrük | Adana Demirspor | 4-0 | 1 - 3 points |
| TR1 | 11/09/21 15:00 | 11/09/21 15:00 | Konyaspor | Altay SK | 3-1 | 1 - 3 points |
| TR1 | 11/09/21 18:00 | 11/09/21 18:00 | Besiktas Istanbul | Yeni Malatyaspor | 3-0 | 1 - 3 points |
| TR1 | 11/09/21 18:00 | 11/09/21 18:00 | Kayserispor | Kasimpasa Istanbul | 2-0 | 1 - 3 points |
| 21/22 | 12/09/21 11:00 | 12/09/21 11:00 | Usakspor | GMG Kastamonuspor | --- | 1 - 3 points |
| 21/22 | 12/09/21 13:00 | 12/09/21 13:00 | Kirsehir Bel.spor | Amed SF | 1-0 | 1 - 3 points |
| 21/22 | 12/09/21 13:30 | 12/09/21 13:30 | Nazilli Bel.spor | Pazarspor | 1-0 | 1 - 3 points |
| TR1 | 12/09/21 15:00 | 12/09/21 15:00 | Caykur Rizespor | Hatayspor | 0-2 | 1 - 3 points |
| TR1 | 12/09/21 15:00 | 12/09/21 15:00 | Fenerbahce Istanbul | Sivasspor | 1-1 | 1 - 3 points |
| 21/22 | 12/09/21 16:00 | 12/09/21 16:00 | Eskisehirspor | Sanliurfaspor | 0-0 | 1 - 3 points |
| 21/22 | 12/09/21 16:00 | 12/09/21 16:00 | Tarsus Idman Yurdu | 24Erzincanspor | 1-0 | 1 - 3 points |
| 21/22 | 12/09/21 16:00 | 12/09/21 16:00 | Isparta 32spor | KT 1922 Konyaspor | 0-0 | 1 - 3 points |
| TR1 | 12/09/21 18:00 | 12/09/21 18:00 | Trabzonspor | Galatasaray Istanbul | 2-2 | 1 - 3 points |
| TR1 | 12/09/21 18:00 | 12/09/21 18:00 | Göztepe Izmir | Istanbul Basaksehir FK | 2-1 | 1 - 3 points |
| 21/22 | 13/09/21 16:00 | 13/09/21 16:00 | Akhisarspor | Bucaspor 1928 | 0-2 | 1 - 3 points |
| TR1 | 13/09/21 18:00 | 13/09/21 18:00 | Alanyaspor | Giresunspor | 1-0 | 1 - 3 points |
| TR1 | 13/09/21 18:00 | 13/09/21 18:00 | Gazisehir Gaziantep FK | Antalyaspor | 2-0 | 1 - 3 points |