Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 02/10/21 14:00 | 02/10/21 14:00 | Lyon OU | Union Bordeaux Bègles | 15-20 | 3 - 10 - 10 |
| 02/10/21 14:00 | 02/10/21 14:00 | Montpellier Hérault RC | Atlantique Stade Rochelais | 21-11 | 4 - 10 - 4 |
| 02/10/21 14:00 | 02/10/21 14:00 | USA Perpignan | Section Paloise | 14-29 | 3 - 10 - 10 |
| 02/10/21 14:00 | 02/10/21 14:00 | CA Brive | Stade Français | 19-12 | 3 - 10 - 7 |
| 02/10/21 16:00 | 02/10/21 16:00 | Biarritz | Stade Toulousain | 11-17 | 7 - 10 - 3 |
| 02/10/21 20:05 | 02/10/21 20:05 | Castres Olympique | RC Toulon | 27-16 | 3 - 10 - 9 |
| 03/10/21 20:05 | 03/10/21 20:05 | ASM Clermont Auvergne | Racing Métro 92 | 26-17 | 3 - 10 - 6 |