Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 30/04/22 14:00 | 30/04/22 14:00 | Lyon OU | Montpellier Hérault RC | 43-20 | 2 - 4 points |
| 30/04/22 16:00 | 30/04/22 16:00 | USA Perpignan | CA Brive | 27-10 | 2 - 4 points |
| 30/04/22 16:00 | 30/04/22 16:00 | ASM Clermont Auvergne | Stade Français | 29-26 | 2 - 4 points |
| 30/04/22 16:00 | 30/04/22 16:00 | Section Paloise | Racing Métro 92 | 21-42 | 2 - 4 points |
| 30/04/22 16:00 | 30/04/22 16:00 | Biarritz | Castres Olympique | 13-48 | 2 - 4 points |
| 30/04/22 20:05 | 30/04/22 20:05 | Stade Toulousain | Atlantique Stade Rochelais | 23-16 | 2 - 4 points |
| 01/05/22 20:05 | 01/05/22 20:05 | Union Bordeaux Bègles | RC Toulon | 16-29 | 2 - 4 points |