Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 26/03/22 14:00 | 26/03/22 14:00 | RC Toulon | ASM Clermont Auvergne | 32-22 | 2 - 4 points |
| 26/03/22 16:00 | 26/03/22 16:00 | Atlantique Stade Rochelais | Racing Métro 92 | 19-0 | 2 - 4 points |
| 26/03/22 16:00 | 26/03/22 16:00 | Section Paloise | USA Perpignan | 27-22 | 2 - 4 points |
| 26/03/22 16:00 | 26/03/22 16:00 | Montpellier Hérault RC | Biarritz | 37-22 | 2 - 4 points |
| 26/03/22 16:00 | 26/03/22 16:00 | CA Brive | Castres Olympique | 28-12 | 2 - 4 points |
| 26/03/22 20:05 | 26/03/22 20:05 | Stade Français | Union Bordeaux Bègles | 18-31 | 2 - 4 points |
| 27/03/22 20:05 | 27/03/22 20:05 | Stade Toulousain | Lyon OU | 27-19 | 2 - 4 points |