Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 10/09/22 14:00 | 10/09/22 14:00 | Lyon OU | Atlantique Stade Rochelais | 21-23 | 2 - 4 points |
| 10/09/22 16:00 | 10/09/22 16:00 | Castres Olympique | Stade Français | 30-20 | 2 - 4 points |
| 10/09/22 16:00 | 10/09/22 16:00 | Aviron Bayonnais | Racing Métro 92 | 31-25 | 2 - 4 points |
| 10/09/22 16:00 | 10/09/22 16:00 | ASM Clermont Auvergne | Section Paloise | 33-24 | 2 - 4 points |
| 10/09/22 16:00 | 10/09/22 16:00 | USA Perpignan | CA Brive | 6-17 | 2 - 4 points |
| 10/09/22 20:05 | 10/09/22 20:05 | Montpellier Hérault RC | Union Bordeaux Bègles | 29-19 | 2 - 4 points |
| 11/09/22 20:05 | 11/09/22 20:05 | Stade Toulousain | RC Toulon | 28-8 | 2 - 4 points |