Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 11/09/21 14:00 | 11/09/21 14:00 | Section Paloise | Lyon OU | 21-17 | 2 - 4 points |
| 11/09/21 14:00 | 11/09/21 14:00 | ASM Clermont Auvergne | Castres Olympique | 30-34 | 2 - 4 points |
| 11/09/21 14:05 | 11/09/21 14:05 | USA Perpignan | Biarritz | 33-20 | 2 - 4 points |
| 11/09/21 14:05 | 11/09/21 14:05 | Montpellier Hérault RC | CA Brive | 39-17 | 2 - 4 points |
| 11/09/21 16:15 | 11/09/21 16:15 | Union Bordeaux Bègles | Stade Français | 37-10 | 2 - 4 points |
| 11/09/21 20:05 | 11/09/21 20:05 | Racing Métro 92 | Atlantique Stade Rochelais | 23-10 | 2 - 4 points |
| 12/09/21 20:05 | 12/09/21 20:05 | Stade Toulousain | RC Toulon | 41-10 | 2 - 4 points |