Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 05/02/22 14:00 | 05/02/22 14:00 | USA Perpignan | Stade Toulousain | 36-13 | 2 - 4 points |
| 05/02/22 16:00 | 05/02/22 16:00 | Montpellier Hérault RC | Section Paloise | 29-12 | 2 - 4 points |
| 05/02/22 16:00 | 05/02/22 16:00 | Racing Métro 92 | CA Brive | 57-19 | 2 - 4 points |
| 05/02/22 16:00 | 05/02/22 16:00 | Lyon OU | Stade Français | 26-22 | 2 - 4 points |
| 05/02/22 20:05 | 05/02/22 20:05 | RC Toulon | Castres Olympique | 10-22 | 2 - 4 points |
| 06/02/22 20:05 | 06/02/22 20:05 | Biarritz | Atlantique Stade Rochelais | 27-24 | 2 - 4 points |
| 13/03/22 20:05 | 13/03/22 20:05 | ASM Clermont Auvergne | Union Bordeaux Bègles | 29-26 | 2 - 4 points |