Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 29/01/22 14:00 | 29/01/22 14:00 | Union Bordeaux Bègles | Castres Olympique | 23-10 | 2 - 4 points |
| 29/01/22 16:00 | 29/01/22 16:00 | CA Brive | Biarritz | 33-10 | 2 - 4 points |
| 29/01/22 16:00 | 29/01/22 16:00 | USA Perpignan | Lyon OU | 23-28 | 2 - 4 points |
| 29/01/22 16:00 | 29/01/22 16:00 | Atlantique Stade Rochelais | Montpellier Hérault RC | 23-29 | 2 - 4 points |
| 29/01/22 20:05 | 29/01/22 20:05 | Stade Toulousain | Racing Métro 92 | 15-20 | 2 - 4 points |
| 30/01/22 17:00 | 30/01/22 17:00 | Section Paloise | ASM Clermont Auvergne | 28-20 | 2 - 4 points |
| 30/01/22 20:05 | 30/01/22 20:05 | Stade Français | RC Toulon | 26-24 | 2 - 4 points |