Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 08/01/22 14:00 | 08/01/22 14:00 | Castres Olympique | Stade Français | 15-9 | 2 - 4 points |
| 08/01/22 16:00 | 08/01/22 16:00 | Biarritz | USA Perpignan | 23-25 | 2 - 4 points |
| 08/01/22 16:00 | 08/01/22 16:00 | Lyon OU | Section Paloise | 35-10 | 2 - 4 points |
| 08/01/22 16:00 | 08/01/22 16:00 | CA Brive | Union Bordeaux Bègles | 19-22 | 2 - 4 points |
| 08/01/22 20:05 | 08/01/22 20:05 | Racing Métro 92 | ASM Clermont Auvergne | 33-28 | 2 - 4 points |
| 19/03/22 16:15 | 19/03/22 16:15 | RC Toulon | Atlantique Stade Rochelais | 41-11 | 2 - 4 points |
| 20/03/22 20:05 | 20/03/22 20:05 | Stade Toulousain | Montpellier Hérault RC | 35-10 | 2 - 4 points |