Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 01/01/22 18:00 | 01/01/22 18:00 | Stade Français | USA Perpignan | 27-17 | 2 - 4 points |
| 01/01/22 20:05 | 01/01/22 20:05 | ASM Clermont Auvergne | Stade Toulousain | 16-13 | 2 - 4 points |
| 02/01/22 13:00 | 02/01/22 13:00 | Section Paloise | CA Brive | 43-20 | 2 - 4 points |
| 02/01/22 15:00 | 02/01/22 15:00 | Union Bordeaux Bègles | Biarritz | 30-27 | 2 - 4 points |
| 02/01/22 17:00 | 02/01/22 17:00 | Castres Olympique | Atlantique Stade Rochelais | 31-30 | 2 - 4 points |
| 02/01/22 20:05 | 02/01/22 20:05 | Lyon OU | Racing Métro 92 | 37-35 | 2 - 4 points |
| 12/03/22 20:05 | 12/03/22 20:05 | Montpellier Hérault RC | RC Toulon | 18-16 | 2 - 4 points |