Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 14/10/22 01:15 | 14/10/22 01:15 | Chicago Bears | Washington Commanders | 7-12 | 3 - 10 - 6 |
| 16/10/22 18:00 | 16/10/22 18:00 | Pittsburgh Steelers | Tampa Bay Buccaneers | 20-18 | 10 - 10 - 3 |
| 16/10/22 18:00 | 16/10/22 18:00 | New Orleans Saints | Cincinnati Bengals | 26-30 | 5 - 10 - 3 |
| 16/10/22 18:00 | 16/10/22 18:00 | New York Giants | Baltimore Ravens | 24-20 | 5 - 10 - 3 |
| 16/10/22 18:00 | 16/10/22 18:00 | Green Bay Packers | New York Jets | 10-27 | 3 - 10 - 10 |
| 16/10/22 18:00 | 16/10/22 18:00 | Miami Dolphins | Minnesota Vikings | 16-24 | 5 - 10 - 3 |
| 16/10/22 18:00 | 16/10/22 18:00 | Indianapolis Colts | Jacksonville Jaguars | 34-27 | 4 - 10 - 5 |
| 16/10/22 18:00 | 16/10/22 18:00 | Atlanta Falcons | San Francisco 49ers | 28-14 | 10 - 10 - 3 |
| 16/10/22 18:00 | 16/10/22 18:00 | Cleveland Browns | New England Patriots | 15-38 | 4 - 10 - 4 |
| 16/10/22 21:05 | 16/10/22 21:05 | Seattle Seahawks | Arizona Cardinals | 19-9 | 4 - 10 - 4 |
| 16/10/22 21:05 | 16/10/22 21:05 | Los Angeles Rams | Carolina Panthers | 24-10 | 3 - 10 - 10 |
| 16/10/22 21:25 | 16/10/22 21:25 | Kansas City Chiefs | Buffalo Bills | 20-24 | 5 - 10 - 4 |
| 17/10/22 01:20 | 17/10/22 01:20 | Philadelphia Eagles | Dallas Cowboys | 26-17 | 3 - 10 - 6 |
| 18/10/22 01:15 | 18/10/22 01:15 | Los Angeles Chargers | Denver Broncos | 19-16OT | 3 - 10 - 10 |