Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 01/10/21 01:20 | 01/10/21 01:20 | Cincinnati Bengals | Jacksonville Jaguars | 24-21 | 3 - 10 - 10 |
| 03/10/21 18:00 | 03/10/21 18:00 | Atlanta Falcons | Washington Football Team | 30-34 | 4 - 10 - 4 |
| 03/10/21 18:00 | 03/10/21 18:00 | Miami Dolphins | Indianapolis Colts | 17-27 | 4 - 10 - 4 |
| 03/10/21 18:00 | 03/10/21 18:00 | Buffalo Bills | Houston Texans | 40-0 | 3 - 10 - 10 |
| 03/10/21 18:00 | 03/10/21 18:00 | Chicago Bears | Detroit Lions | 24-14 | 4 - 10 - 5 |
| 03/10/21 18:00 | 03/10/21 18:00 | Minnesota Vikings | Cleveland Browns | 7-14 | 5 - 10 - 4 |
| 03/10/21 18:00 | 03/10/21 18:00 | New Orleans Saints | New York Giants | 21-27OT | 3 - 10 - 10 |
| 03/10/21 18:00 | 03/10/21 18:00 | Dallas Cowboys | Carolina Panthers | 36-28 | 3 - 10 - 5 |
| 03/10/21 18:00 | 03/10/21 18:00 | Philadelphia Eagles | Kansas City Chiefs | 30-42 | 10 - 10 - 3 |
| 03/10/21 18:00 | 03/10/21 18:00 | New York Jets | Tennessee Titans | 27-24OT | 10 - 10 - 3 |
| 03/10/21 21:05 | 03/10/21 21:05 | Los Angeles Rams | Arizona Cardinals | 20-37 | 3 - 10 - 9 |
| 03/10/21 21:05 | 03/10/21 21:05 | San Francisco 49ers | Seattle Seahawks | 21-28 | 4 - 10 - 4 |
| 03/10/21 21:25 | 03/10/21 21:25 | Denver Broncos | Baltimore Ravens | 7-23 | 6 - 10 - 3 |
| 03/10/21 21:25 | 03/10/21 21:25 | Green Bay Packers | Pittsburgh Steelers | 27-17 | 3 - 10 - 9 |
| 04/10/21 01:20 | 04/10/21 01:20 | New England Patriots | Tampa Bay Buccaneers | 17-19 | 10 - 10 - 3 |
| 05/10/21 01:15 | 05/10/21 01:15 | Los Angeles Chargers | Las Vegas Raiders | 28-14 | 4 - 10 - 4 |