Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 03/12/21 01:20 | 03/12/21 01:20 | New Orleans Saints | Dallas Cowboys | 17-27 | 7 - 10 - 3 |
| 05/12/21 18:00 | 05/12/21 18:00 | Atlanta Falcons | Tampa Bay Buccaneers | 17-30 | 10 - 10 - 3 |
| 05/12/21 18:00 | 05/12/21 18:00 | Cincinnati Bengals | Los Angeles Chargers | 22-41 | 3 - 10 - 5 |
| 05/12/21 18:00 | 05/12/21 18:00 | Chicago Bears | Arizona Cardinals | 22-33 | 10 - 10 - 3 |
| 05/12/21 18:00 | 05/12/21 18:00 | New York Jets | Philadelphia Eagles | 18-33 | 7 - 10 - 3 |
| 05/12/21 18:00 | 05/12/21 18:00 | Detroit Lions | Minnesota Vikings | 29-27 | 10 - 10 - 3 |
| 05/12/21 18:00 | 05/12/21 18:00 | Houston Texans | Indianapolis Colts | 0-31 | 10 - 10 - 3 |
| 05/12/21 18:00 | 05/12/21 18:00 | Miami Dolphins | New York Giants | 20-9 | 3 - 10 - 7 |
| 05/12/21 21:05 | 05/12/21 21:05 | Los Angeles Rams | Jacksonville Jaguars | 37-7 | 3 - 10 - 10 |
| 05/12/21 21:05 | 05/12/21 21:05 | Las Vegas Raiders | Washington Football Team | 15-17 | 3 - 10 - 5 |
| 05/12/21 21:25 | 05/12/21 21:25 | Seattle Seahawks | San Francisco 49ers | 30-23 | 5 - 10 - 3 |
| 05/12/21 21:25 | 05/12/21 21:25 | Pittsburgh Steelers | Baltimore Ravens | 20-19 | 10 - 10 - 3 |
| 06/12/21 01:20 | 06/12/21 01:20 | Kansas City Chiefs | Denver Broncos | 22-9 | 3 - 10 - 10 |
| 07/12/21 01:15 | 07/12/21 01:15 | Buffalo Bills | New England Patriots | 10-14 | 4 - 10 - 4 |