Schedule
| Competition | Date | Dead line | Home | Away | Group | Result | Points rule |
|---|---|---|---|---|---|---|---|
| CL | 19/10/21 20:00 | 19/10/21 19:45 | Paris St. Germain | RB Leipzig | Group A | 3-2 | 1 - 2 points |
| CL | 19/10/21 20:00 | 19/10/21 19:45 | Ajax Amsterdam | Borussia Dortmund | Group C | 4-0 | 1 - 2 points |
| CL | 20/10/21 17:45 | 20/10/21 17:30 | FC Red Bull Salzburg | VfL Wolfsburg | Group G | 3-1 | 1 - 2 points |
| CL | 20/10/21 20:00 | 20/10/21 19:45 | Benfica Lisbon | FC Bayern Munich | Group E | 0-4 | 1 - 2 points |
| EL | 21/10/21 17:45 | 21/10/21 17:30 | Real Betis Sevilla | Bayer 04 Leverkusen | Group G | 1-1 | 1 - 2 points |
| ConfL | 21/10/21 17:45 | 21/10/21 17:30 | Feyenoord Rotterdam | 1. FC Union Berlin | Group E | 3-1 | 1 - 2 points |
| EL | 21/10/21 20:00 | 21/10/21 19:45 | Eintracht Frankfurt | Olympiakos Piräus | Group D | 3-1 | 1 - 2 points |
| 2.BL | 22/10/21 17:30 | 22/10/21 17:15 | SC Paderborn 07 | Hamburger SV | - | 1-2 | 1 - 2 points |
| GER1 | 22/10/21 19:30 | 22/10/21 19:15 | FSV Mainz 05 | FC Augsburg | - | 4-1 | 1 - 2 points |
| GER1 | 23/10/21 14:30 | 23/10/21 14:15 | RB Leipzig | SpVgg Greuther Fürth | - | 4-1 | 1 - 2 points |
| GER1 | 23/10/21 14:30 | 23/10/21 14:15 | FC Bayern Munich | 1899 Hoffenheim | - | 4-0 | 1 - 2 points |
| GER1 | 23/10/21 14:30 | 23/10/21 14:15 | Arminia Bielefeld | Borussia Dortmund | - | 1-3 | 1 - 2 points |
| GER1 | 23/10/21 14:30 | 23/10/21 14:15 | VfL Wolfsburg | SC Freiburg | - | 0-2 | 1 - 2 points |
| GER1 | 23/10/21 17:30 | 23/10/21 17:15 | Hertha BSC | Bor. Mönchengladbach | - | 1-0 | 1 - 2 points |
| 2.BL | 24/10/21 12:30 | 24/10/21 12:15 | SV Sandhausen | Werder Bremen | - | 2-2 | 1 - 2 points |
| GER1 | 24/10/21 14:30 | 24/10/21 14:15 | 1. FC Köln | Bayer 04 Leverkusen | - | 2-2 | 1 - 2 points |
| GER1 | 24/10/21 16:30 | 24/10/21 16:15 | VfB Stuttgart | 1. FC Union Berlin | - | 1-1 | 1 - 2 points |
| GER1 | 24/10/21 18:30 | 24/10/21 18:15 | VfL Bochum | Eintracht Frankfurt | - | 2-0 | 1 - 2 points |