Schedule
| Competition | Date | Dead line | Home | Away | Group | Result | Points rule |
|---|---|---|---|---|---|---|---|
| CL | 28/09/21 20:00 | 28/09/21 19:45 | RB Leipzig | Club Brugge | Group A | 1-2 | 1 - 2 points |
| CL | 28/09/21 20:00 | 28/09/21 19:45 | Borussia Dortmund | Sporting Lisbon | Group C | 1-0 | 1 - 2 points |
| CL | 29/09/21 20:00 | 29/09/21 19:45 | VfL Wolfsburg | FC Sevilla | Group G | 1-1 | 1 - 2 points |
| CL | 29/09/21 20:00 | 29/09/21 19:45 | FC Bayern Munich | Dynamo Kiew | Group E | 5-0 | 1 - 2 points |
| EL | 30/09/21 17:45 | 30/09/21 17:30 | Royal Antwerp FC | Eintracht Frankfurt | Group D | 0-1 | 1 - 2 points |
| EL | 30/09/21 20:00 | 30/09/21 19:45 | Celtic Glasgow | Bayer 04 Leverkusen | Group G | 0-4 | 1 - 2 points |
| ConfL | 30/09/21 20:00 | 30/09/21 19:45 | 1. FC Union Berlin | Maccabi Haifa | Group E | 3-0 | 1 - 2 points |
| 2.BL | 01/10/21 17:30 | 01/10/21 17:15 | Werder Bremen | 1. FC Heidenheim 1846 | - | 3-0 | 1 - 2 points |
| GER1 | 01/10/21 19:30 | 01/10/21 19:15 | 1. FC Köln | SpVgg Greuther Fürth | - | 3-1 | 1 - 2 points |
| GER1 | 02/10/21 14:30 | 02/10/21 14:15 | Hertha BSC | SC Freiburg | - | 1-2 | 1 - 2 points |
| GER1 | 02/10/21 14:30 | 02/10/21 14:15 | VfB Stuttgart | 1899 Hoffenheim | - | 3-1 | 1 - 2 points |
| GER1 | 02/10/21 14:30 | 02/10/21 14:15 | VfL Wolfsburg | Bor. Mönchengladbach | - | 1-3 | 1 - 2 points |
| GER1 | 02/10/21 14:30 | 02/10/21 14:15 | Borussia Dortmund | FC Augsburg | - | 2-1 | 1 - 2 points |
| GER1 | 02/10/21 17:30 | 02/10/21 17:15 | RB Leipzig | VfL Bochum | - | 3-0 | 1 - 2 points |
| 2.BL | 02/10/21 19:30 | 02/10/21 19:15 | 1. FC Nürnberg | Hannover 96 | - | 0-0 | 1 - 2 points |
| GER1 | 03/10/21 14:30 | 03/10/21 14:15 | FSV Mainz 05 | 1. FC Union Berlin | - | 1-2 | 1 - 2 points |
| GER1 | 03/10/21 16:30 | 03/10/21 16:15 | FC Bayern Munich | Eintracht Frankfurt | - | 1-2 | 1 - 2 points |
| GER1 | 03/10/21 18:30 | 03/10/21 18:15 | Arminia Bielefeld | Bayer 04 Leverkusen | - | 0-4 | 1 - 2 points |