Schedule
| Competition | Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|---|
| CL | 12/04/22 20:00 | 12/04/22 19:45 | FC Bayern Munich | FC Villarreal | 1-1 | 1 - 2 points |
| EL | 14/04/22 17:45 | 14/04/22 17:30 | Atalanta Bergamo | RB Leipzig | 0-2 | 1 - 2 points |
| EL | 14/04/22 20:00 | 14/04/22 19:45 | FC Barcelona | Eintracht Frankfurt | 2-3 | 1 - 2 points |
| GER1 | 16/04/22 14:30 | 16/04/22 14:15 | FC Augsburg | Hertha BSC | 0-1 | 1 - 2 points |
| GER1 | 16/04/22 14:30 | 16/04/22 14:15 | FSV Mainz 05 | VfB Stuttgart | 0-0 | 1 - 2 points |
| GER1 | 16/04/22 14:30 | 16/04/22 14:15 | SC Freiburg | VfL Bochum | 3-0 | 1 - 2 points |
| GER1 | 16/04/22 14:30 | 16/04/22 14:15 | Borussia Dortmund | VfL Wolfsburg | 6-1 | 1 - 2 points |
| GER1 | 16/04/22 17:30 | 16/04/22 17:15 | Bor. Mönchengladbach | 1. FC Köln | 1-3 | 1 - 2 points |
| 2.BL | 17/04/22 12:30 | 17/04/22 12:15 | Werder Bremen | 1. FC Nürnberg | 1-1 | 1 - 2 points |
| 2.BL | 17/04/22 12:30 | 17/04/22 12:15 | SV Darmstadt 98 | FC Schalke 04 | 2-5 | 1 - 2 points |
| GER1 | 17/04/22 14:30 | 17/04/22 14:15 | Arminia Bielefeld | FC Bayern Munich | 0-3 | 1 - 2 points |
| GER1 | 17/04/22 16:30 | 17/04/22 16:15 | 1899 Hoffenheim | SpVgg Greuther Fürth | 0-0 | 1 - 2 points |
| GER1 | 17/04/22 16:30 | 17/04/22 16:15 | 1. FC Union Berlin | Eintracht Frankfurt | 2-0 | 1 - 2 points |
| GER1 | 17/04/22 18:30 | 17/04/22 18:15 | Bayer 04 Leverkusen | RB Leipzig | 0-1 | 1 - 2 points |