| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 02/09/22 20:00 | 02/09/22 20:00 | Celta Vigo | FC Cadiz | 3-0 | 2 - 4 points |
| 03/09/22 13:00 | 03/09/22 13:00 | RCD Mallorca | FC Girona | 1-1 | 2 - 4 points |
| 03/09/22 15:15 | 03/09/22 15:15 | Real Madrid | Real Betis Sevilla | 2-1 | 2 - 4 points |
| 03/09/22 17:30 | 03/09/22 17:30 | Real Sociedad | Atletico Madrid | 1-1 | 2 - 4 points |
| 03/09/22 20:00 | 03/09/22 20:00 | FC Sevilla | FC Barcelona | 0-3 | 2 - 4 points |
| 04/09/22 13:00 | 04/09/22 13:00 | CA Osasuna | Rayo Vallecano | 2-1 | 2 - 4 points |
| 04/09/22 15:15 | 04/09/22 15:15 | Athletic Bilbao | Espanyol Barcelona | 0-1 | 2 - 4 points |
| 04/09/22 17:30 | 04/09/22 17:30 | FC Villarreal | FC Elche | 4-0 | 2 - 4 points |
| 04/09/22 20:00 | 04/09/22 20:00 | FC Valencia | FC Getafe | 5-1 | 2 - 4 points |
| 05/09/22 20:00 | 05/09/22 20:00 | Real Valladolid | UD Almeria | 1-0 | 2 - 4 points |