Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 20/11/21 12:30 | 20/11/21 12:30 | Leicester City | Chelsea FC | 0-3 | 7 - 6 - 3 |
| 20/11/21 15:00 | 20/11/21 15:00 | Wolverhampton Wanderers | West Ham United | 1-0 | 7 - 5 - 3 |
| 20/11/21 15:00 | 20/11/21 15:00 | Burnley FC | Crystal Palace | 3-3 | 5 - 4 - 4 |
| 20/11/21 15:00 | 20/11/21 15:00 | Newcastle United | Brentford FC | 3-3 | 4 - 5 - 6 |
| 20/11/21 15:00 | 20/11/21 15:00 | Norwich City | Southampton FC | 2-1 | 7 - 6 - 3 |
| 20/11/21 15:00 | 20/11/21 15:00 | Watford FC | Manchester United | 4-1 | 7 - 7 - 3 |
| 20/11/21 15:00 | 20/11/21 15:00 | Aston Villa | Brighton and Hove Albion | 2-0 | 4 - 5 - 6 |
| 20/11/21 17:30 | 20/11/21 17:30 | Liverpool FC | Arsenal FC | 4-0 | 3 - 7 - 7 |
| 21/11/21 14:00 | 21/11/21 14:00 | Manchester City | Everton FC | 3-0 | 3 - 7 - 7 |
| 21/11/21 16:30 | 21/11/21 16:30 | Tottenham Hotspur | Leeds United | 2-1 | 3 - 7 - 7 |