Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 21/01/25 15:30 | 21/01/25 15:30 | Galatasaray Istanbul | Dynamo Kiew | --- | 2 - 4 points |
| 22/01/25 15:30 | 22/01/25 15:30 | Besiktas Istanbul | Athletic Bilbao | --- | 2 - 4 points |
| 23/01/25 17:45 | 23/01/25 17:45 | AZ Alkmaar | AS Roma | --- | 2 - 4 points |
| 23/01/25 17:45 | 23/01/25 17:45 | Malmö FF | FC Twente Enschede | --- | 2 - 4 points |
| 23/01/25 17:45 | 23/01/25 17:45 | FK Bodö/Glimt | Maccabi Tel Aviv | --- | 2 - 4 points |
| 23/01/25 17:45 | 23/01/25 17:45 | Qarabag | FCSB Bukarest | --- | 2 - 4 points |
| 23/01/25 17:45 | 23/01/25 17:45 | Viktoria Plzen | RSC Anderlecht | --- | 2 - 4 points |
| 23/01/25 17:45 | 23/01/25 17:45 | 1899 Hoffenheim | Tottenham Hotspur | --- | 2 - 4 points |
| 23/01/25 17:45 | 23/01/25 17:45 | FC Porto | Olympiakos Piräus | --- | 2 - 4 points |
| 23/01/25 17:45 | 23/01/25 17:45 | Fenerbahce Istanbul | Olympique Lyon | --- | 2 - 4 points |
| 23/01/25 20:00 | 23/01/25 20:00 | Rigas Futbola Skola | Ajax Amsterdam | --- | 2 - 4 points |
| 23/01/25 20:00 | 23/01/25 20:00 | PFC Ludogorets Razgrad | FC Midtjylland | --- | 2 - 4 points |
| 23/01/25 20:00 | 23/01/25 20:00 | Royale Union Saint-Gilloise | Sporting Braga | --- | 2 - 4 points |
| 23/01/25 20:00 | 23/01/25 20:00 | IF Elfsborg Boras | OGC Nice | --- | 2 - 4 points |
| 23/01/25 20:00 | 23/01/25 20:00 | Eintracht Frankfurt | Ferencvaros Budapest | --- | 2 - 4 points |
| 23/01/25 20:00 | 23/01/25 20:00 | Manchester United | Glasgow Rangers | --- | 2 - 4 points |
| 23/01/25 20:00 | 23/01/25 20:00 | Lazio Rom | Real Sociedad | --- | 2 - 4 points |
| 23/01/25 20:00 | 23/01/25 20:00 | PAOK Saloniki | Slavia Prag | --- | 2 - 4 points |