Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 28/11/24 17:45 | 28/11/24 17:45 | Lazio Rom | PFC Ludogorets Razgrad | --- | 2 - 4 points |
| 28/11/24 17:45 | 28/11/24 17:45 | Dynamo Kiew | Viktoria Plzen | --- | 2 - 4 points |
| 28/11/24 17:45 | 28/11/24 17:45 | Qarabag | Olympique Lyon | --- | 2 - 4 points |
| 28/11/24 17:45 | 28/11/24 17:45 | Besiktas Istanbul | Maccabi Tel Aviv | --- | 2 - 4 points |
| 28/11/24 17:45 | 28/11/24 17:45 | Rigas Futbola Skola | PAOK Saloniki | --- | 2 - 4 points |
| 28/11/24 17:45 | 28/11/24 17:45 | RSC Anderlecht | FC Porto | --- | 2 - 4 points |
| 28/11/24 17:45 | 28/11/24 17:45 | Athletic Bilbao | IF Elfsborg Boras | --- | 2 - 4 points |
| 28/11/24 17:45 | 28/11/24 17:45 | AZ Alkmaar | Galatasaray Istanbul | --- | 2 - 4 points |
| 28/11/24 20:00 | 28/11/24 20:00 | Slavia Prag | Fenerbahce Istanbul | --- | 2 - 4 points |
| 28/11/24 20:00 | 28/11/24 20:00 | Manchester United | FK Bodö/Glimt | --- | 2 - 4 points |
| 28/11/24 20:00 | 28/11/24 20:00 | Tottenham Hotspur | AS Roma | --- | 2 - 4 points |
| 28/11/24 20:00 | 28/11/24 20:00 | Ferencvaros Budapest | Malmö FF | --- | 2 - 4 points |
| 28/11/24 20:00 | 28/11/24 20:00 | Sporting Braga | 1899 Hoffenheim | --- | 2 - 4 points |
| 28/11/24 20:00 | 28/11/24 20:00 | Real Sociedad | Ajax Amsterdam | --- | 2 - 4 points |
| 28/11/24 20:00 | 28/11/24 20:00 | FC Midtjylland | Eintracht Frankfurt | --- | 2 - 4 points |
| 28/11/24 20:00 | 28/11/24 20:00 | FCSB Bukarest | Olympiakos Piräus | --- | 2 - 4 points |
| 28/11/24 20:00 | 28/11/24 20:00 | OGC Nice | Glasgow Rangers | --- | 2 - 4 points |
| 28/11/24 20:00 | 28/11/24 20:00 | FC Twente Enschede | Royale Union Saint-Gilloise | --- | 2 - 4 points |