| Date | Home | Away | Group | Result |
|---|---|---|---|---|
| 14/12/23 17:45 | Bayer 04 Leverkusen | Molde FK | Group H | 5-1 |
| 14/12/23 17:45 | Qarabag | BK Häcken | Group H | 2-1 |
| 14/12/23 17:45 | AS Roma | Sheriff Tiraspol | Group G | 3-0 |
| 14/12/23 17:45 | Slavia Prag | Servette FC Genève | Group G | 4-0 |
| 14/12/23 17:45 | Royale Union Saint-Gilloise | Liverpool FC | Group E | 2-1 |
| 14/12/23 17:45 | Linzer ASK | FC Toulouse | Group E | 1-2 |
| 14/12/23 17:45 | Panathinaikos Athens | Maccabi Haifa | Group F | 1-2 |
| 14/12/23 17:45 | Stade Rennes | FC Villarreal | Group F | 2-3 |
| 14/12/23 20:00 | West Ham United | SC Freiburg | Group A | 2-0 |
| 14/12/23 20:00 | Olympiakos Piräus | TSC Backa Topola | Group A | 5-2 |
| 14/12/23 20:00 | Brighton and Hove Albion | Olympique Marseille | Group B | 1-0 |
| 14/12/23 20:00 | Ajax Amsterdam | AEK Athens | Group B | 3-1 |
| 14/12/23 20:00 | Real Betis Sevilla | Glasgow Rangers | Group C | 2-3 |
| 14/12/23 20:00 | Aris Limassol | Sparta Prag | Group C | 1-3 |
| 14/12/23 20:00 | Sporting Lisbon | SK Sturm Graz | Group D | 3-0 |
| 14/12/23 20:00 | KS Rakow Czestochowa | Atalanta Bergamo | Group D | 0-4 |