| Date | Home | Away | Result |
|---|---|---|---|
| 23/10/24 15:30 | Sporting Braga | FK Bodö/Glimt | --- |
| 23/10/24 15:30 | Galatasaray Istanbul | IF Elfsborg Boras | --- |
| 24/10/24 17:45 | AS Roma | Dynamo Kiew | --- |
| 24/10/24 17:45 | Eintracht Frankfurt | Rigas Futbola Skola | --- |
| 24/10/24 17:45 | Maccabi Tel Aviv | Real Sociedad | --- |
| 24/10/24 17:45 | Ferencvaros Budapest | OGC Nice | --- |
| 24/10/24 17:45 | PAOK Saloniki | Viktoria Plzen | --- |
| 24/10/24 17:45 | FC Midtjylland | Royale Union Saint-Gilloise | --- |
| 24/10/24 17:45 | Qarabag | Ajax Amsterdam | --- |
| 24/10/24 20:00 | Fenerbahce Istanbul | Manchester United | --- |
| 24/10/24 20:00 | Glasgow Rangers | FCSB Bukarest | --- |
| 24/10/24 20:00 | FC Porto | 1899 Hoffenheim | --- |
| 24/10/24 20:00 | Tottenham Hotspur | AZ Alkmaar | --- |
| 24/10/24 20:00 | Olympique Lyon | Besiktas Istanbul | --- |
| 24/10/24 20:00 | Malmö FF | Olympiakos Piräus | --- |
| 24/10/24 20:00 | FC Twente Enschede | Lazio Rom | --- |
| 24/10/24 20:00 | RSC Anderlecht | PFC Ludogorets Razgrad | --- |
| 24/10/24 20:00 | Athletic Bilbao | Slavia Prag | --- |